Healthcare Articles/Resources

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The Health Benefits of Sauna

https://chriskresser.com/the-health-benefits-of-saunas/

How Sauna Therapy Can Prevent & Reverse Chronic Disease, with Brian Richards

https://chriskresser.com/how-sauna-therapy-can-prevent-reverse-chronic-disease-with-brian-richard

Aging/Longevity

Khazaeli AA, Tatar M, Pletcher SD, Curtsinger JW

Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance

J Gerontol A Biol Sci Med Sci. 1997 Jan; 52(1):B48-52 

Laukkanen JA, Kunutsor SK

The multifaceted benefits of passive heat therapies for extending the healthspan: A comprehensive review with a focus on Finnish sauna

Temperature (Austin). 2024 Feb 25;11(1):27-51. doi: 10.1080/23328940.2023.2300623. PMID: 38577299; PMCID: PMC10989710.

Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA

Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study

BMC Med. 2018 Nov 29;16(1):219. doi: 10.1186/s12916-018-1198-0. PMID: 30486813; PMCID: PMC6262976.

Lithgow GJ, White TM, Melov S, Johnson TE

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

Proc Natl Acad Sci USA. 1995 Aug 1; 92(16):7540-4 

Tatar M, Khazaeli AA, Curtsinger JW

Chaperoning extended life

Nature. 1997 Nov 6; 390(6655):30

Yeager RL, Oleske DA, Sanders RA, Watkins JB 3rd, Eells JT, Henshel DS

Melatonin as a principal component of red light therapy

Med Hypotheses. 2007;69(2):372-6

Zimmerman, S. and Reiter, R

Melatonin and the Optics of the Human Body

Melatonin Research. 2, 1 (Feb. 2019), 138-160 

 Antimicrobial

St Denis TG, Dai T, Izikson L, Astrakas C, Anderson RR, Hamblin MR, Tegos GP.

All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov-Dec;2(6):509-20. doi: 10.4161/viru.2.6.17889. Epub 2011 Nov 1. PMID: 21971183; PMCID: PMC3260545. 

 Bain/Memory/Cognitive Function

Clark IA, Vissel B

Inflammation-sleep interface in brain disease: TNF, insulin, orexin

J Neuroinflammation. 2014 Mar 21; 11:51 

Duveau V, Arthaud S, Serre H, Rougier A, Le Gal La Salle G

Transient hyperthermia protects against subsequent seizures and epilepsy-induced cell damage in the rat

Neurobiol Dis. 2005 Jun-Jul; 19(1-2):142-9 

Gomes LE, Dalmarco EM, André ES

The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model

Photomed Laser Surg. 2012 Nov; 30(11):642-7 

Hamblin MR

Shining light on the head: Photobiomodulation for brain disorders

BBA Clin. 2016 Oct 1; 6:113–124

Laukkanen T, Kunutsor S, Kauhanen J, Laukkanen JA

Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men

Age Ageing. 2017 Mar 1; 46(2):245-249 

Lundgren J, Smith ML, Blennow G, Siesjö BK

Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage

Exp Brain Res. 1994; 99(1):43-55

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Rojas JC, Gonzalez-Lima F

Low-level light therapy of the eye and brain

Eye and Brain. 2011; 3:49–67

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Salehpour F, Farajdokht F, Erfani M, Sadigh-Eteghad S, Shotorbani SS, Hamblin MR, Karimi P, Rasta SH, Mahmoudi J

Transcranial near-infrared photobiomodulation attenuates memory impairment and hippocampal oxidative stress in sleep-deprived mice.

Brain Res. 2018 Mar 1; 1682:36-43

Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety

Behavioral and Brain Functions : BBF. 2009; 5:46 

Xin L, Geller EB, Adler MW

Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain

J Pharmacol Exp Ther. 1997 Apr; 281(1):499-507 

Yang M, Yang Z, Wang P, Sun Z

Current application and future directions of photobiomodulation in central nervous diseases.

Neural Regen Res. 2021; 16(6):1177-1185 

Zimmerman, S. and Reiter, R

Melatonin and the Optics of the Human Body

Melatonin Research. 2, 1 (Feb. 2019), 138-160 

American Cancer Society

Cancer Facts and Figures 2021

Atlanta: American Cancer Society 2021 

Atanackovic D, Nierhaus A, Neumeier M, Hossfeld DK, Hegewisch-Becker S

41.8 degrees C whole body hyperthermia as an adjunct to chemotherapy induces prolonged T cell activation in patients with various malignant diseases

Cancer Immunol Immunother. 2002 Dec; 51(11-12):603-13 

Barni S, Bertone V, Silvotti MG, Freitas I, Mathé G, Pontiggia P

Lysosomal exocytosis induced by hyperthermia: a new model of cancer death. III. Effect on liver metastasis

Biomed Pharmacother. 1996; 50:79-84

Burd R, Dziedzic TS, Xu Y, Caligiuri MA, Subjeck JR, Repasky EA

Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia

J Cell Physiol 1998;177(1):137-147

Fessenden J

Tuning light to kill deep cancer tumors

UMass Medical School Communications 41913 

Hamblin MR, Nelson ST, Strahan JR

Photobiomodulation and Cancer: What Is the Truth?

Photomed Laser Surg. 2018 May; 36(5):241-245 

Issels RD

Hyperthermia As Used In Cancer Tumor Treatment

Immuno-Oncology

Liu XL, Ma F, Zhou CX, Huang M, Gong HY, Xie GY, Hu CH

Therapeutic effect of whole body hyperthermia combined with chemotherapy in patients with advanced cancer [Article in Chinese]

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 Jun;31(3):350-2 

Manjili MH, Wang XY, Park J, Macdonald IJ, Li Y, Van Schie RC, Subjeck JR

Cancer immunotherapy: stress proteins and hyperthermia

Int J Hyperthermia. 2002 Nov-Dec; 18(6):506-20 

Mitsunaga M, Ogawa M, Kosaka N, Rosenblum LT, Choyke PL, Kobayashi H

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Nat Med. 2011 Nov 6; 17:1685–91

Moss RW

The Life and Times of John Beard, DSc (1858-1924)

Integr Cancer Ther. 2008 Dec; 7(4):229-51 

National Cancer Institute

Hyperthermia in Cancer Treatment

National Cancer Institute. 2021 June 17 

Niwa Y, Kawahira K, Matsumoto K

Effect of far infrared ray emitting products and stones on human leukocyte functions, lipid peroxidation, the growth of tumor on mice, drug-induced hepatitis rat, and clinical course and serum lipid peroxide levels of rheumatoid arthritis patients [in Japanese]

Japanese Journal of Inflammation. 1996; 16:425-436 

Reiter RJ, Ma Q, Sharma R

Melatonin in Mitochondria: Mitigating Clear and Present Dangers

Physiology (Bethesda). 2020 Mar 1;35(2):86-95 

Shen RN, Hornback NB, Shidnia H, Shupe RE, Brahmi Z

Whole-body hyperthermia decreases lung metastases in lung tumor-bearing mice, possibly via a mechanism involving natural killer cells

J Clin Immunol 1987 May;7(3):246-53

Srivastava PK

Roles of Heat Shock Proteins [Supplement to Article Could Our Own Proteins Be Used to Help Us Fight Cancer?]

Sci Am 2008(July)

Wilson L

Infrared Sauna Therapy For Cancer

The Foundation for Advancement in Cancer Therapy. 2020 May 7

Kihara T, Biro S, Imamura M, Yoshifuku S, Takasaki K, Ikeda Y, Otuji Y, Minagoe S, Toyama Y and Tei C (2002)

Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure

J Am Coll Cardiol 2002 Mar 6;39(5):754-9. doi: 10.1016/s0735-1097(01)01824-1 

J Cell Physiol 1998;177(1):137-147

Costa RJ, Crockford MJ, Moore JP, Walsh NP

Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition

Eur J Sport Sci 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19 

Gilligan DM, Panza JM, Kilcoyne CM, et al

Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation

Circulation Dec 1994, Vol 90, No 6

Ihsan F R

Low-level laser therapy accelerates collateral circulation and enhances microcirculation

Photomed Laser Surg 2005 Jun;23(3):289-94 

Imamura M, Biro S, Kihara T, Yoshifuku S, Takasaki K, Otsuji Y, Minagoe S, Toyama Y and Tei C (2001)

Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors

J Am Coll Cardiol 2001; 38, 1083–1088 

Kihara T, Biro S, Imamura M, Yoshifuku S, Takasaki K, Ikeda Y, Otuji Y, Minagoe S, Toyama Y and Tei C (2002)

Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure

J Am Coll Cardiol 2002 Mar 6;39(5):754-9. doi: 10.1016/s0735-1097(01)01824-1 

Kihara T, Miyata M, Fukudome T, Ikeda Y, Shinsato T, Kubozono T, Fujita S, Kuwahata S, Hamasaki S, Torii H, Lee S, Toda H, Tei C

Waon therapy improves the prognosis of patients with chronic heart failure

J Cardiol 2009 Apr;53(2):214-8. doi: 10.1016/j.jjcc.2008.11.005. Epub 2009 Jan 18. 

Laatikainen T, Salminen K, Kohvakka A, Pettersson J

Response of plasma endorphins, prolactin and catecholamines in women to intense heat in a sauna

Eur J Appl Physiol Occup Physiol 1988;57(1):98-102 

Laukkanen T, Hassan Khan H, Zaccardi F, Laukkanen J

Association Between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality Events

JAMA Intern Med 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187. 

Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA

Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study

BMC Med. 2018 Nov 29;16(1):219. doi: 10.1186/s12916-018-1198-0. PMID: 30486813; PMCID: PMC6262976.

Maegawa Y, Itoh T, Hosokawa T, Yaegashi K, Nishi M

Effects of near-infrared low-level laser irradiation on microcirculation

Lasers Surg Med 2000;27(5):427-37. doi: 10.1002/1096-9101(2000)27:5<427::AID-LSM1004>3.0.CO;2-A. 

Savard GK, Nielsen B, Laszczynska J, Larsen BE, Saltin B

Muscle blood flow is not reduced in humans during moderate exercise and heat stress

J Appl Physiol (1985) 1988 Feb;64(2):649-57 

Yang M, Yang Z, Wang P, Sun Z

Current application and future directions of photobiomodulation in central nervous diseases.

Neural Regen Res. 2021; 16(6):1177-1185 

Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M

Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism

J Mol Cell Cardiol 2009 Jan;46(1):4-14. doi: 10.1016/j.yjmcc.2008.09.707 

Barni S, Bertone V, Silvotti MG, Freitas I, Mathé G, Pontiggia P

Lysosomal exocytosis induced by hyperthermia: a new model of cancer death. III. Effect on liver metastasis

Biomed Pharmacother. 1996; 50:79-84

Barolet D, Boucher A

Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series

Lasers Surg Med 2010 Aug;42(6):597-601. doi: 10.1002/lsm.20952 

Cecchini MA, Root DE, Rachunow JR, Gelb PM

Chemical exposures at the World Trade Center: Use of the Hubbard sauna detoxification regimen to improve the health status of New York City rescue workers exposed to toxicants

Townsend Lett 2006; April:58–65

Colbert D, MD

Curbing the Toxic Onslaught. Detoxification III

NutriNews, Douglas Laboratories 2005, Autumn 

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT

Therapeutic photobiomodulation for methanol-induced retinal toxicity

Proc Natl Acad Sci U S A 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100 

Gard ZR, Brown EJ

Literature review and comparison studies of sauna/hyperthermia in detoxification: Part II

Townsend Lett 1992; July:650–660

Pedersen BK

Muscle as a secretory organ

Compr Physiol 2013 Jul;3(3):1337-62. doi: 10.1002/cphy.c120033 

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Wilson L, MD

Sauna Therapy for Detoxification and Healing

Prescott, AZ: LD Wilson Consultants, Inc 2011 

Wong-Riley M, Liang H, et al

Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins

The Journal of Biological Chemistry February 11, 2005, 280: 4761-4771. doi: 10.1074/jbc.M409650200 

DeBruyne LK, Pinna K, Whitney EN

Nutrition and Diet Therapy

Belmont, CA: Cengage Learning 8th edition, June 20 2011: 187 

Maniam J, Morris MJ

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

Psychoneuroendocrinology 2010 Nov;35(10):1553-64. doi: 10.1016/j.psyneuen.2010.05.012. Epub 2010 Jul 1. 

Barni S, Bertone V, Silvotti MG, Freitas I, Mathé G, Pontiggia P

Lysosomal exocytosis induced by hyperthermia: a new model of cancer death. III. Effect on liver metastasis

Biomed Pharmacother. 1996; 50:79-84

Beauvoit B, Kitai T, and Chance B

Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach

Biophys J 1994 Dec;67(6):2501-10

Bibikova A, Oron U

Promotion of muscle regeneration in the toad (Bufo viridis) gastrocnemius muscle by low-energy laser irradiation

Anat Rec 1993 Mar;235(3):374-80

Cecchini MA, Root DE, Rachunow JR, Gelb PM

Chemical exposures at the World Trade Center: Use of the Hubbard sauna detoxification regimen to improve the health status of New York City rescue workers exposed to toxicants

Townsend Lett 2006; April:58–65

Colbert D, MD

Curbing the Toxic Onslaught. Detoxification III

NutriNews, Douglas Laboratories 2005, Autumn 

DeBruyne LK, Pinna K, Whitney EN

Nutrition and Diet Therapy

Belmont, CA: Cengage Learning 8th edition, June 20 2011: 187 

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT

Therapeutic photobiomodulation for methanol-induced retinal toxicity

Proc Natl Acad Sci U S A 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100 

Gard ZR, Brown EJ

Literature review and comparison studies of sauna/hyperthermia in detoxification: Part II

Townsend Lett 1992; July:650–660

Maniam J, Morris MJ

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

Psychoneuroendocrinology 2010 Nov;35(10):1553-64. doi: 10.1016/j.psyneuen.2010.05.012. Epub 2010 Jul 1. 

Pedersen BK

Muscle as a secretory organ

Compr Physiol 2013 Jul;3(3):1337-62. doi: 10.1002/cphy.c120033 

Wei Q, Hill WD, Su Y, Huang S, Dong Z

Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injury

Am J Physiol Renal Physiol 2011;301(1):F162-F170. doi:10.1152/ajprenal.00438.2010 

Wilson L, MD

Sauna Therapy for Detoxification and Healing

Prescott, AZ: LD Wilson Consultants, Inc 2011 

Wong-Riley M, Liang H, et al

Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins

The Journal of Biological Chemistry February 11, 2005, 280: 4761-4771. doi: 10.1074/jbc.M409650200 

Yu W, Naim JO, McGowan M, Ippolito K, Lanzafame RJ

Photomodulation of Oxidative Metabolism and Electron Chain Enzymes in Rat Liver Mitochondria

Photochem Photobiol 1997 Dec;66(6):866-71 

Castex-Rizzi N, Lachgar S, Charvéron M, Gall Y

Implication of VEGF, steroid hormones and neuropeptides in hair follicle cell responses [Article in French]

Ann Dermatol Venereol 2002 May;129(5 Pt 2):783-6 

Chow LS, Albright RC, Bigelow ML, Toffolo G, Cobelli C, Nair KS

Mechanism of insulin’s anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures

Am J Physiol Endocrinol Metab 2006 Oct;291(4):E729-36. Epub 2006 May 16 

Christensen SE, Jørgensen OL, et al

Characterization of Growth Hormone Release in Response to External Heating

Acta Endocrinol (Copenh) 1984 Nov; 107(3): 295-301 

Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

J Biol Chem 1995 May 19;270(20):12109-16 

Felsing NE, Brasel JA, Cooper DM

Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men

J Clin Endocrinol Metab 1992 Jul;75(1):157-62 

Ftaiti F, Jemni M, Kacem A, Zaouali MA, Tabka Z, Zbidi A, Grélot L

Effect of hyperthermia and physical activity on circulating growth hormone

Appl Physiol Nutr Metab 2008 Oct;33(5):880-7. doi: 10.1139/H08-073 

Goekint M, Roelands B, Heyman E, Njemini R, Meeusen R

Influence of citalopram and environmental temperature on exercise-induced changes in BDNF

Neurosci Lett 2011 Apr 25;494(2):150-4. doi: 10.1016/j.neulet.2011.03.001. Epub 2011 Mar 6 

Healy ML, Gibney J, Russell-Jones DL, Pentecost C, Croos P, Sönksen PH, Umpleby AM

High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes

J Clin Endocrinol Metab 2003 Nov;88(11):5221-6 

Ho KY, Veldhuis JD, Johnson ML, et al

Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man

Journal of Clinical Investigation 1988;81(4):968-975 

Höfling DB, Chavantes MC, Juliano AB, Cerri GG, Romão R, Yoshimura EM, Chammas MC

Low-level laser therapy in chronic autoimmune thyroiditis: a pilot study

Lasers Surg Med 2010 Aug;42(6):589-96 

Höfling DB, Chavantes MC, Juliano AG, Cerri GG, Knobel M, Yoshimura EM, Chammas MC

Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo-controlled clinical trial

Lasers Med Sci 2013 May;28(3):743-53 

Kukkonen-Harjula K, Oja P, Laustiola K, Vuori I, Jolkkonen J, Siitonen S, Vapaatalo H

Haemodynamic and hormonal responses to heat exposure in a Finnish sauna bath

Eur J Appl Physiol Occup Physiol 1989;58(5):543-50 

Leppäluoto J, Huttunen P, Hirvonen J, Väänänen A, Tuominen M, Vuori J

Endocrine effects of repeated sauna bathing

Acta Physiol Scand 1986 Nov;128(3):467-70 

Velloso CP

Regulation of muscle mass by growth hormone and IGF-I

British Journal of Pharmacology 2008;154(3):557-568. doi:10.1038/bjp.2008.153 

Costa RJ, Crockford MJ, Moore JP, Walsh NP

Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition

Eur J Sport Sci 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19 

Demura S, Noguchi T, Matsuzawa J

Comparison in the Effect of Linear Polarized Near-Infrared Light Irradiation and Light Exercise on Shoulder Joint Flexibility

J Mol Cell Cardiol Jan 2009; 46(1): 4–14. doi: 10.1016/j.yjmcc.2008.09.707 

Felsing NE, Brasel JA, Cooper DM

Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men

J Clin Endocrinol Metab 1992 Jul;75(1):157-62 

Gilligan DM, Panza JM, Kilcoyne CM, et al

Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation

Circulation Dec 1994, Vol 90, No 6

Goekint M, Roelands B, Heyman E, Njemini R, Meeusen R

Influence of citalopram and environmental temperature on exercise-induced changes in BDNF

Neurosci Lett 2011 Apr 25;494(2):150-4. doi: 10.1016/j.neulet.2011.03.001. Epub 2011 Mar 6 

Healy ML, Gibney J, Russell-Jones DL, Pentecost C, Croos P, Sönksen PH, Umpleby AM

High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes

J Clin Endocrinol Metab 2003 Nov;88(11):5221-6 

King DS, Costill DL, Fink WJ, Hargreaves M, Fielding RA

Muscle metabolism during exercise in the heat in unacclimatized and acclimatized humans

J Appl Physiol (1985) 1985 Nov;59(5):1350-4. doi: 10.1152/jappl.1985.59.5.1350. 

Maniam J, Morris MJ

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

Psychoneuroendocrinology 2010 Nov;35(10):1553-64. doi: 10.1016/j.psyneuen.2010.05.012. Epub 2010 Jul 1. 

Möckel F, Hoffmann G, Obermüller R, Drobnik W, Schmitz G

Influence of water-filtered infrared-A (wIRA) on reduction of local fat and body weight by physical exercise

Ger Med Sci 2006; 4: Doc05

Savard GK, Nielsen B, Laszczynska J, Larsen BE, Saltin B

Muscle blood flow is not reduced in humans during moderate exercise and heat stress

J Appl Physiol (1985) 1988 Feb;64(2):649-57 

Sawka MN, Wenger BC, Pandolf KB

Thermoregulatory Responses to Acute Exercise‐Heat Stress and Heat Acclimation

Compr Physiol 2011, Supplement 14: Handbook of Physiology, Environmental Physiology: 157-185. First published in print 1996. doi: 10.1002/cphy.cp040109 

Scoon GS, Hopkins WG, Mayhew S, Cotter JD

Effect of post-exercise sauna bathing on the endurance performance of competitive male runners

J Sci Med Sport 2007 Aug;10(4):259-62. Epub 2006 Jul 31 

Van Praag H, Christie BR, Sejnowski TJ, Gage FH

Running enhances neurogenesis, learning, and long-term potentiation in mice

Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13427-13431 

Wigal SB, Nemet D, Swanson JM, Regino R, Trampush J, Ziegler MG, Cooper DM

Catecholamine response to exercise in children with attention deficit hyperactivity disorder

Pediatr Res 2003 May;53(5):756-61. Epub 2003 Mar 5 

Zhao J, Tian Y, Nie J, Xu J, Liu D

Red light and the sleep quality and endurance performance of Chinese female basketball players

J Athl Train. 2012 Nov-Dec;47(6):673-8 

Ablon G

Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings

Photomed Laser Surg 2010 Feb;28(1):141-6. doi: 10.1089/pho.2009.2484. 

Barolet D, Roberge CJ, Auger FA, Boucher A, Germain L

Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study

J Invest Dermatol 2009 Dec;129(12):2751-9. doi: 10.1038/jid.2009.186. Epub 2009 Jul 9 

Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simões A, de Paula Eduardo C

Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection

Photomed Laser Surg 2010 Feb;28(1):135-9. doi: 10.1089/pho.2008.2458 

Branham GH, Thomas JR

Rejuvenation of the skin surface: chemical peel and dermabrasion

Facial Plast Surg 1996 Apr;12(2):125-33 

Calles C, Schneider M, Macaluso F, Benesova T, Krutmann J, Schroeder P

Infrared A radiation influences the skin fibroblast transcriptome: mechanisms and consequences

J Invest Dermatol 2010 Jun;130(6):1524-36. doi: 10.1038/jid.2010.9. Epub 2010 Feb 4 

Castex-Rizzi N, Lachgar S, Charvéron M, Gall Y

Implication of VEGF, steroid hormones and neuropeptides in hair follicle cell responses [Article in French]

Ann Dermatol Venereol 2002 May;129(5 Pt 2):783-6 

Cherniaev, IuS

Investigation of the permeability of human skin to infrared radiation [Article in Russian]

Gig Sanit 1965 Dec;30(12):20-4

Cunliffe WJ, Goulden V

Phototherapy and acne vulgaris

Br J Dermatol 2000 May;142(5):855-6

Eduardo Cde P, Bezinelli LM, Eduardo Fde P, da Graça Lopes RM, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M

Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up

Lasers Med Sci 2012 Sep;27(5):1077-83. doi: 10.1007/s10103-011-1019-6. Epub 2011 Nov 16 

Goldberg DJ, Russell BA

Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris

J Cosmet Laser Ther 2006 Jun;8(2):71-5 

Landthaler M, Haina D, Waidelich W

Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light [Article in German]

Fortschr Med 1983 Jun 9;101(22):1039-41 

Lee SY, Park KH, Choi JW, Kwon JK, Lee DR, Shin MS, Lee JS, You CE, Park MY

A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings

J Photochem Photobiol B 2007 Jul 27;88(1):51-67. Epub 2007 May 1 

Lee SY, You CE, Park MY

Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV

Lasers Surg Med 2007 Feb;39(2):180-8 

Muñoz Sanchez PJ, Capote Femenías JL, Díaz Tejeda A, Tunér J

The effect of 670-nm low laser therapy on herpes simplex type 1

Photomed Laser Surg 2012 Jan;30(1):37-40. doi: 10.1089/pho.2011.3076. Epub 2011 Nov 2 

Otberg N, Finner AM, Shapiro J

Androgenetic alopecia

Endocrinol Metab Clin North Am 2007 Jun;36(2):379-98 

Papageorgiou P, Katsambas A, Chu A

Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris

Br J Dermatol 2000 May;142(5):973-8

Rossi AB, Vergnanini AL

Cellulite: a review

J Eur Acad Dermatol Venereol 2000(July); 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x 

Sadick NS

Handheld LED array device in the treatment of acne vulgaris

J Drugs Dermatol 2008 Apr;7(4):347-50 

Satino JL, Markou M

Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

International Journal of Cosmetic Surgery and Aesthetic Dermatology August 2003, 5(2): 113-117. doi:10.1089/153082003769591209 

Schindl A, Neumann R

Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study

J Invest Dermatol 1999 Aug;113(2):221-3 

Schroeder P, Calles C, Benesova T, Macaluso F, Krutmann J

Photoprotection beyond ultraviolet radiation–effective sun protection has to include protection against infrared A radiation-induced skin damage

Skin Pharmacol Physiol 2010;23(1):15-7. doi: 10.1159/000257259. Epub 2010 Jan 14 

Shukla S, Sahu K, Verma Y, Rao KD, Dube A, Gupta PK

Effect of helium-neon laser irradiation on hair follicle growth cycle of Swiss albino mice

Skin Pharmacol Physiol 2010;23(2):79-85. doi: 10.1159/000265678. Epub 2009 Dec 14 

Sriprachya-Anunt S, Fitzpatrick RE, Goldman MP, Smith SR

Infections complicating pulsed carbon dioxide laser resurfacing for photoaged facial skin

Dermatol Surg 1997 Jul;23(7):527-35; discussion 535-6 

Takema Y, Yorimoto Y, Kawai M, Imokawa G

Age-related changes in the elastic properties and thickness of human facial skin

Br J Dermatol 1994 Nov;131(5):641-8

Tanaka Y, Matsuo K, Yuzuriha S

Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians

Clinical, Cosmetic and Investigational Dermatology 2011;4:123-130. doi:10.2147/CCID.S22841 

Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ

Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata

Lasers Med Sci 2012 Mar;27(2):431-6. doi: 10.1007/s10103-011-0953-7. Epub 2011 Jul 9 

Barolet D, Christiaens F, Hamblin MR

Infrared and skin: Friend or foe

J Photochem Photobiol B. 2016 Feb; 155:78-85 

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT

Therapeutic photobiomodulation for methanol-induced retinal toxicity

Proc Natl Acad Sci U S A 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100 

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT

Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy

Mitochondrion 2004 Sep;4(5-6):559-67 

Ham WT Jr, Mueller HA, Ruffolo JJ Jr, Clarke AM

Sensitivity of the retina to radiation damage as a function of wavelength

Photochem Photobiol 1979 Apr;29(4):735-43 

Lydahl E, Philipson B

Infrared radiation and cataract II. Epidemiologic investigation of glass workers

Acta Ophthalmol (Copenh) 1984 Dec;62(6):976-92 

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Rojas JC, Gonzalez-Lima F

Low-level light therapy of the eye and brain

Eye and Brain. 2011; 3:49–67

Shinhmar H, Hogg C, Neveu M, Jeffery G

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Sci Rep. 2021; 11(22872)

Voke , J

Radiation effects on the eye

Optometry Today 1999; 8:30-35

Zhu Q, Xiao S, Hua Z, Yang D, Hu M, Zhu YT, Zhong H

Near Infrared (NIR) Light Therapy of Eye Diseases: A Review

International journal of medical sciences. 2021 Jan 1; 18(1):109-119 

Abou-Hala AZ, Barbosa DG, Marcos RL, et al

Effects of the Infrared Lamp Illumination during the Process of Muscle Fatigue in Rats

RAZ ARCH BIOL TECHNOL 01/2007; 50(3). doi: 10.1590/S1516-89132007000300006 

Ferraresi C, Hamblin MR, Parizotto NA

Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light

Photonics and lasers in medicine 2012;1(4):267-286. doi:10.1515/plm-2012-0032 

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Inger R, Bennie J, Davies TW, Gaston KJ

Potential biological and ecological effects of flickering artificial light

PLoS One. 2014 May 29;9(5):e98631. doi: 10.1371/journal.pone.0098631. eCollection 2014. 

Zhu Q, Xiao S, Hua Z, Yang D, Hu M, Zhu YT, Zhong H

Near Infrared (NIR) Light Therapy of Eye Diseases: A Review

International journal of medical sciences. 2021 Jan 1; 18(1):109-119 

Castex-Rizzi N, Lachgar S, Charvéron M, Gall Y

Implication of VEGF, steroid hormones and neuropeptides in hair follicle cell responses [Article in French]

Ann Dermatol Venereol 2002 May;129(5 Pt 2):783-6 

Leavitt M, Charles G, Heyman E, Michaels D

HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: A randomized, double-blind, sham device-controlled, multicentre trial

Clin Drug Investig 2009;29(5):283-92. doi: 10.2165/00044011-200929050-00001 

Otberg N, Finner AM, Shapiro J

Androgenetic alopecia

Endocrinol Metab Clin North Am 2007 Jun;36(2):379-98 

Satino JL, Markou M

Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

International Journal of Cosmetic Surgery and Aesthetic Dermatology August 2003, 5(2): 113-117. doi:10.1089/153082003769591209 

Shukla S, Sahu K, Verma Y, Rao KD, Dube A, Gupta PK

Effect of helium-neon laser irradiation on hair follicle growth cycle of Swiss albino mice

Skin Pharmacol Physiol 2010;23(2):79-85. doi: 10.1159/000265678. Epub 2009 Dec 14 

Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ

Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata

Lasers Med Sci 2012 Mar;27(2):431-6. doi: 10.1007/s10103-011-0953-7. Epub 2011 Jul 9

Christman JV, Gisolfi CV

Heat acclimation: role of norepinephrine in the anterior hypothalamus

J Appl Physiol (1985) 1985 Jun;58(6):1923-8 

Costa RJ, Crockford MJ, Moore JP, Walsh NP

Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition

Eur J Sport Sci 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19 

Garrett AT, Creasy R, Rehrer NJ, Patterson MJ, Cotter JD

Effectiveness of short-term heat acclimation for highly trained athletes

Eur J Appl Physiol 2012 May;112(5):1827-37. doi: 10.1007/s00421-011-2153-3. Epub 2011 Sep 14 

Kirwan JP, Costill DL, Kuipers H, Burrell MJ, Fink WJ, Kovaleski JE, Fielding RA

Substrate utilization in leg muscle of men after heat acclimation

J Appl Physiol (1985) 1987 Jul;63(1):31-5. doi: 10.1152/jappl.1987.63.1.31. 

Kuennen M, Gillum T, Dokladny K, Bedrick E, Schneider S, Moseley P

Thermotolerance and heat acclimation may share a common mechanism in humans

Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R524-33. doi: 10.1152/ajpregu.00039.2011. Epub 2011 May 25. 

Lithgow GJ, White TM, Melov S, Johnson TE

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

Proc Natl Acad Sci USA. 1995 Aug 1; 92(16):7540-4 

Sawka MN, Wenger BC, Pandolf KB

Thermoregulatory Responses to Acute Exercise‐Heat Stress and Heat Acclimation

Compr Physiol 2011, Supplement 14: Handbook of Physiology, Environmental Physiology: 157-185. First published in print 1996. doi: 10.1002/cphy.cp040109 

Yamada PM, Amorim FT, Moseley P, Robergs R, Schneider SM

Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans

J Appl Physiol (1985) 2007 Oct;103(4):1196-204. Epub 2007 Jul 5 

American Cancer Society

Cancer Facts and Figures 2021

Atlanta: American Cancer Society 2021 

Atanackovic D, Nierhaus A, Neumeier M, Hossfeld DK, Hegewisch-Becker S

41.8 degrees C whole body hyperthermia as an adjunct to chemotherapy induces prolonged T cell activation in patients with various malignant diseases

Cancer Immunol Immunother. 2002 Dec; 51(11-12):603-13 

Barni S, Bertone V, Silvotti MG, Freitas I, Mathé G, Pontiggia P

Lysosomal exocytosis induced by hyperthermia: a new model of cancer death. III. Effect on liver metastasis

Biomed Pharmacother. 1996; 50:79-84

Burd R, Dziedzic TS, Xu Y, Caligiuri MA, Subjeck JR, Repasky EA

Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia

J Cell Physiol 1998;177(1):137-147

Christensen SE, Jørgensen OL, et al

Characterization of Growth Hormone Release in Response to External Heating

Acta Endocrinol (Copenh) 1984 Nov; 107(3): 295-301 

Christman JV, Gisolfi CV

Heat acclimation: role of norepinephrine in the anterior hypothalamus

J Appl Physiol (1985) 1985 Jun;58(6):1923-8 

Costa RJ, Crockford MJ, Moore JP, Walsh NP

Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition

Eur J Sport Sci 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19 

Duveau V, Arthaud S, Serre H, Rougier A, Le Gal La Salle G

Transient hyperthermia protects against subsequent seizures and epilepsy-induced cell damage in the rat

Neurobiol Dis. 2005 Jun-Jul; 19(1-2):142-9 

Felsing NE, Brasel JA, Cooper DM

Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men

J Clin Endocrinol Metab 1992 Jul;75(1):157-62 

Ftaiti F, Jemni M, Kacem A, Zaouali MA, Tabka Z, Zbidi A, Grélot L

Effect of hyperthermia and physical activity on circulating growth hormone

Appl Physiol Nutr Metab 2008 Oct;33(5):880-7. doi: 10.1139/H08-073 

Gard ZR, Brown EJ

Literature review and comparison studies of sauna/hyperthermia in detoxification: Part II

Townsend Lett 1992; July:650–660

Garrett AT, Creasy R, Rehrer NJ, Patterson MJ, Cotter JD

Effectiveness of short-term heat acclimation for highly trained athletes

Eur J Appl Physiol 2012 May;112(5):1827-37. doi: 10.1007/s00421-011-2153-3. Epub 2011 Sep 14 

Goekint M, Roelands B, Heyman E, Njemini R, Meeusen R

Influence of citalopram and environmental temperature on exercise-induced changes in BDNF

Neurosci Lett 2011 Apr 25;494(2):150-4. doi: 10.1016/j.neulet.2011.03.001. Epub 2011 Mar 6 

Goldmann, H

Kritische und experimentelle Untersuchungen über den sogenannten Ultrarotstar der Kaninchen und den Feuerstar [Text in German]

Arch. Ophthal Dec 1930; 125: 313-402 

Hannuksela M L, Ellahham S

Benefits and Risks of Sauna Bathing

Am J Med 2001 Feb;110(2):118-26

Imamura M, Biro S, Kihara T, Yoshifuku S, Takasaki K, Otsuji Y, Minagoe S, Toyama Y and Tei C (2001)

Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors

J Am Coll Cardiol 2001; 38, 1083–1088 

Issels RD

Hyperthermia As Used In Cancer Tumor Treatment

Immuno-Oncology

Khazaeli AA, Tatar M, Pletcher SD, Curtsinger JW

Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance

J Gerontol A Biol Sci Med Sci. 1997 Jan; 52(1):B48-52 

Kihara T, Biro S, Imamura M, Yoshifuku S, Takasaki K, Ikeda Y, Otuji Y, Minagoe S, Toyama Y and Tei C (2002)

Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure

J Am Coll Cardiol 2002 Mar 6;39(5):754-9. doi: 10.1016/s0735-1097(01)01824-1 

King DS, Costill DL, Fink WJ, Hargreaves M, Fielding RA

Muscle metabolism during exercise in the heat in unacclimatized and acclimatized humans

J Appl Physiol (1985) 1985 Nov;59(5):1350-4. doi: 10.1152/jappl.1985.59.5.1350. 

Kirwan JP, Costill DL, Kuipers H, Burrell MJ, Fink WJ, Kovaleski JE, Fielding RA

Substrate utilization in leg muscle of men after heat acclimation

J Appl Physiol (1985) 1987 Jul;63(1):31-5. doi: 10.1152/jappl.1987.63.1.31. 

Kokura S, Adachi S, Manabe E, Mizushima K, Hattori T, Okuda T, Nakabe N, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T

Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice

Int J Hyperthermia 2007 May;23(3):259-65. doi: 10.1080/02656730601176824. 

Koltyn KF, Robins HI, Schmitt CL, Cohen JD, Morgan WP

Changes in mood state following whole-body hyperthermia

Int J Hyperthermia 1992 May-Jun;8(3):305-7 

Kuennen M, Gillum T, Dokladny K, Bedrick E, Schneider S, Moseley P

Thermotolerance and heat acclimation may share a common mechanism in humans

Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R524-33. doi: 10.1152/ajpregu.00039.2011. Epub 2011 May 25. 

Kukkonen-Harjula K, Oja P, Laustiola K, Vuori I, Jolkkonen J, Siitonen S, Vapaatalo H

Haemodynamic and hormonal responses to heat exposure in a Finnish sauna bath

Eur J Appl Physiol Occup Physiol 1989;58(5):543-50 

Laatikainen T, Salminen K, Kohvakka A, Pettersson J

Response of plasma endorphins, prolactin and catecholamines in women to intense heat in a sauna

Eur J Appl Physiol Occup Physiol 1988;57(1):98-102 

Laukkanen T, Hassan Khan H, Zaccardi F, Laukkanen J

Association Between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality Events

JAMA Intern Med 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187. 

Laukkanen T, Kunutsor S, Kauhanen J, Laukkanen JA

Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men

Age Ageing. 2017 Mar 1; 46(2):245-249 

Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA

Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study

BMC Med. 2018 Nov 29;16(1):219. doi: 10.1186/s12916-018-1198-0. PMID: 30486813; PMCID: PMC6262976.

Lecker SH, Goldberg AL, Mitch WE

Protein degradation by the ubiquitin-proteasome pathway in normal and disease states

J Am Soc Nephrol 2006 Jul;17(7):1807-19. doi: 10.1681/ASN.2006010083. Epub 2006 May 31. 

Leppäluoto J, Huttunen P, Hirvonen J, Väänänen A, Tuominen M, Vuori J

Endocrine effects of repeated sauna bathing

Acta Physiol Scand 1986 Nov;128(3):467-70 

Lithgow GJ, White TM, Melov S, Johnson TE

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

Proc Natl Acad Sci USA. 1995 Aug 1; 92(16):7540-4 

Liu XL, Ma F, Zhou CX, Huang M, Gong HY, Xie GY, Hu CH

Therapeutic effect of whole body hyperthermia combined with chemotherapy in patients with advanced cancer [Article in Chinese]

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 Jun;31(3):350-2 

Lundgren J, Smith ML, Blennow G, Siesjö BK

Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage

Exp Brain Res. 1994; 99(1):43-55

Manjili MH, Wang XY, Park J, Macdonald IJ, Li Y, Van Schie RC, Subjeck JR

Cancer immunotherapy: stress proteins and hyperthermia

Int J Hyperthermia. 2002 Nov-Dec; 18(6):506-20 

Moseley PL

Heat shock proteins and heat adaptation of the whole organism

J Appl Physiol (1985) 1997 Nov;83(5):1413-7 

Naito H, Powers SK, Demirel HA, Sugiura T, Dodd SL, Aoki J

Heat stress attenuates skeletal muscle atrophy in hindlimb-unweighted rats

J Appl Physiol (1985) 2000 Jan;88(1):359-63 

Narita M, Khotib J, Suzuki M, Ozaki S, Yajima Y, Suzuki T

Heterologous mu-opioid receptor adaptation by repeated stimulation of kappa-opioid receptor: up-regulation of G-protein activation and antinociception

J Neurochem 2003 Jun;85(5):1171-9

Nath KA, Balla G, Vercellotti GM, et al

Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat

Journal of Clinical Investigation 1992;90(1):267-270 

National Cancer Institute

Hyperthermia in Cancer Treatment

National Cancer Institute. 2021 June 17 

Ostberg JR, Repasky EA

Emerging evidence indicates that physiologically relevant thermal stress regulates dendritic cell function

Cancer Immunol Immunother 38470

Reisinger E, Wendelin I, Gasser R, Halwachs G, Wilders-Truschnig M, Krejs G

Antibiotics and increased temperature against Borrelia burgdorferi in vitro

Scand J Infect Dis 1996;28(2):155-7

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Rossi AB, Vergnanini AL

Cellulite: a review

J Eur Acad Dermatol Venereol 2000(July); 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x 

Savard GK, Nielsen B, Laszczynska J, Larsen BE, Saltin B

Muscle blood flow is not reduced in humans during moderate exercise and heat stress

J Appl Physiol (1985) 1988 Feb;64(2):649-57 

Sawka MN, Wenger BC, Pandolf KB

Thermoregulatory Responses to Acute Exercise‐Heat Stress and Heat Acclimation

Compr Physiol 2011, Supplement 14: Handbook of Physiology, Environmental Physiology: 157-185. First published in print 1996. doi: 10.1002/cphy.cp040109 

Scoon GS, Hopkins WG, Mayhew S, Cotter JD

Effect of post-exercise sauna bathing on the endurance performance of competitive male runners

J Sci Med Sport 2007 Aug;10(4):259-62. Epub 2006 Jul 31 

Selsby JT, Dodd SL

Heat treatment reduces oxidative stress and protects muscle mass during immobilization

Am J Physiol Regul Integr Comp Physiol 2005 Jul;289(1):R134-9. Epub 2005 Mar 10 

Selsby JT, Rother S, Tsuda S, Pracash O, Quindry J, Dodd SL

Intermittent hyperthermia enhances skeletal muscle regrowth and attenuates oxidative damage following reloading

J Appl Physiol (1985) 2007 Apr;102(4):1702-7. Epub 2006 Nov 16 

Shen RN, Hornback NB, Shidnia H, Shupe RE, Brahmi Z

Whole-body hyperthermia decreases lung metastases in lung tumor-bearing mice, possibly via a mechanism involving natural killer cells

J Clin Immunol 1987 May;7(3):246-53

Singh R, Kølvraa S, Bross P, et al

Anti-Inflammatory Heat Shock Protein 70 Genes are Positively Associated with Human Survival

Current pharmaceutical design 2010;16(7):796-801 

Srivastava PK

Roles of Heat Shock Proteins [Supplement to Article Could Our Own Proteins Be Used to Help Us Fight Cancer?]

Sci Am 2008(July)

Sylver N

The Holistic Handbook of Sauna Therapy

Center for Frequency Education (2003) ISBN-13: 978-0967249179 

Tatar M, Khazaeli AA, Curtsinger JW

Chaperoning extended life

Nature. 1997 Nov 6; 390(6655):30

Wikipedia

Hyperthermia Therapy

Wilson L

Infrared Sauna Therapy For Cancer

The Foundation for Advancement in Cancer Therapy. 2020 May 7 

Wilson L, MD

Sauna Therapy for Detoxification and Healing

Prescott, AZ: LD Wilson Consultants, Inc 2011 

Xin L, Geller EB, Adler MW

Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain

J Pharmacol Exp Ther. 1997 Apr; 281(1):499-507 

Yamada PM, Amorim FT, Moseley P, Robergs R, Schneider SM

Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans

J Appl Physiol (1985) 2007 Oct;103(4):1196-204. Epub 2007 Jul 5 

Yenari MA, Giffard RG, Sapolsky RM, Steinberg GK

The neuroprotective potential of heat shock protein 70 (HSP70)

Mol Med Today 1999 Dec;5(12):525-31

Cecchini MA, Root DE, Rachunow JR, Gelb PM

Chemical exposures at the World Trade Center: Use of the Hubbard sauna detoxification regimen to improve the health status of New York City rescue workers exposed to toxicants

Townsend Lett 2006; April:58–65

Burd R, Dziedzic TS, Xu Y, Caligiuri MA, Subjeck JR, Repasky EA

Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia

J Cell Physiol 1998;177(1):137-147

Hanna R, Dalvi S, Sălăgean T, Bordea IR, Benedicenti S

Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical Review

Antioxidants (Basel) 2020;9(9):875

Manjili MH, Wang XY, Park J, Macdonald IJ, Li Y, Van Schie RC, Subjeck JR

Cancer immunotherapy: stress proteins and hyperthermia

Int J Hyperthermia. 2002 Nov-Dec; 18(6):506-20 

Meneguzzo DT, Lopes LA, Pallota R, Soares-Ferreira L, Lopes-Martins RÁ, Ribeiro MS

Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes

Lasers Med Sci 2013 May;28(3):973-80. doi: 10.1007/s10103-012-1163-7. Epub 2012 Aug 23 

Mitsunaga M, Ogawa M, Kosaka N, Rosenblum LT, Choyke PL, Kobayashi H

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Nat Med. 2011 Nov 6; 17:1685–91

Porcella S, Schwan T

Borrelia burgdorferi and Treponema pallidum: a comparison of functional genomics, environmental adaptations, and pathogenic mechanisms

J Clin Invest 2001;107(6):651–656. doi:10.1172/JCI12484 

St Denis TG, Dai T, Izikson L, Astrakas C, Anderson RR, Hamblin MR, Tegos GP.

All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov-Dec;2(6):509-20. doi: 10.4161/viru.2.6.17889. Epub 2011 Nov 1. PMID: 21971183; PMCID: PMC3260545.

Clark IA, Vissel B

Inflammation-sleep interface in brain disease: TNF, insulin, orexin

J Neuroinflammation. 2014 Mar 21; 11:51 

Guillet C, Masgrau A, Walrand S, Boirie Y

Impaired protein metabolism: interlinks between obesity, insulin resistance and inflammation

Obes Rev 2012 Dec;13 Suppl 2:51-7. doi: 10.1111/j.1467-789X.2012.01037.x 

Hamblin M

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

AIMS Biophysics 4(3): 337-361. (May 2017); DOI: 10.3934/biophy.2017.3.337 

Ibe O, Morency E, Sosa P,Burkow-Heikkinen L

The role of near-infrared light-emitting diodes in aging adults related to inflammation

Healthy Aging Research 2015, 4:24; 10 April 2015 

Kim SG, MD, Shin IH, PhD, Choi CH, MD, and Choe JY, MD

Anti-Inflammatory Effect of Near-Infrared Irradiated Cell Culture Media [Article in Korean]

Korean J Lab Med 2009 Aug;29(4):338-44. doi: 10.3343/kjlm.2009.29.4.338. 

Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA

Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study

BMC Med. 2018 Nov 29;16(1):219. doi: 10.1186/s12916-018-1198-0. PMID: 30486813; PMCID: PMC6262976.

Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J

IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells

J Interferon Cytokine Res 2009 May;29(5):273-84. doi: 10.1089/jir.2008.0076 

Singh R, Kølvraa S, Bross P, et al

Anti-Inflammatory Heat Shock Protein 70 Genes are Positively Associated with Human Survival

Current pharmaceutical design 2010;16(7):796-801 

Bjordal JM, Lopes-Martins RA, Joensen J, et al

A systematic review with procedural assessments and meta-analysis of Low Level Laser Therapy in lateral elbow tendinopathy (tennis elbow)

BMC Musculoskeletal Disorders 2008;9:75. doi:10.1186/1471-2474-9-75 

Demura S, Noguchi T, Matsuzawa J

Comparison in the Effect of Linear Polarized Near-Infrared Light Irradiation and Light Exercise on Shoulder Joint Flexibility

J Mol Cell Cardiol Jan 2009; 46(1): 4–14. doi: 10.1016/j.yjmcc.2008.09.707 

Demura S, Yamaji S, Ikemoto Y

Effect of linear polarized near-infrared light irradiation on flexibility of shoulder and ankle joints

J Sports Med Phys Fitness 2002 Dec;42(4):438-45 

Jang H, Lee H

Meta-Analysis of Pain Relief Effects by Laser Irradiation on Joint Areas

Photomed Laser Surg 2012;30(8):405-417. doi: 10.1089/pho.2012.3240 

de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H

Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon

Lasers Med Sci 2015 Jan;30(1):153-8. doi: 10.1007/s10103-014-1636-y. Epub 2014 Jul 29 

Hamblin MR

Shining light on the head: Photobiomodulation for brain disorders

BBA Clin. 2016 Oct 1; 6:113–124

Van Praag H, Christie BR, Sejnowski TJ, Gage FH

Running enhances neurogenesis, learning, and long-term potentiation in mice

Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13427-13431 

Ablon G

Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings

Photomed Laser Surg 2010 Feb;28(1):141-6. doi: 10.1089/pho.2009.2484. 

Alster TS, Tanzi EL

Cellulite treatment using a novel combination radiofrequency, infrared light, and mechanical tissue manipulation device

J Cosmet Laser Ther 2005 Jun;7(2):81-5 

American Society for Testing and Materials

Reference Solar Spectral Irradiance: Air Mass 1.5

ASTM 41545

Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring

Semin Cutan Med Surg 2013 Mar;32(1):41-52 

Azeemi S, Raza M

A Critical Analysis of Chromotherapy and Its Scientific Evolution

Evidence-Based Complementary and Alternative Medicine Vol. 2, no. 4, pp. 481-488, 2005. doi :10.1093/ecam/neh137 

Barolet D, Boucher A

Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series

Lasers Surg Med 2010 Aug;42(6):597-601. doi: 10.1002/lsm.20952 

Barolet D, Christiaens F, Hamblin MR

Infrared and skin: Friend or foe

J Photochem Photobiol B. 2016 Feb; 155:78-85 

Barolet D, Roberge CJ, Auger FA, Boucher A, Germain L

Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study

J Invest Dermatol 2009 Dec;129(12):2751-9. doi: 10.1038/jid.2009.186. Epub 2009 Jul 9 

Beauvoit B, Kitai T, and Chance B

Contribution of the mitochondrial compartment to the optical properties of the rat liver: a theoretical and practical approach

Biophys J 1994 Dec;67(6):2501-10

Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simões A, de Paula Eduardo C

Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection

Photomed Laser Surg 2010 Feb;28(1):135-9. doi: 10.1089/pho.2008.2458 

Bibikova A, Oron U

Promotion of muscle regeneration in the toad (Bufo viridis) gastrocnemius muscle by low-energy laser irradiation

Anat Rec 1993 Mar;235(3):374-80

Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA

Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials

Photomed Laser Surg 2006 Apr;24(2):158-68 

Bjordal JM, Lopes-Martins RA, Joensen J, et al

A systematic review with procedural assessments and meta-analysis of Low Level Laser Therapy in lateral elbow tendinopathy (tennis elbow)

BMC Musculoskeletal Disorders 2008;9:75. doi:10.1186/1471-2474-9-75 

Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, Yu Y, Greenway FL

Efficacy of low-level laser therapy for body contouring and spot fat reduction

Obes Surg 2011 Jun;21(6):722-9. doi: 10.1007/s11695-010-0126-y 

Chow RT, Johnson MI, PhD, Lopes-Martins R, Bjordal JM

Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials

Lancet 2009 Dec 5;374(9705):1897-908. doi: 10.1016/S0140-6736(09)61522-1. Epub 2009 Nov 13 

Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR

The Nuts and Bolts of Low-level Laser (Light) Therapy

Ann Biomed Eng 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7. Epub 2011 Nov 2 

Cooper CE, Springett R

Measurement of Cytochrome Oxidase and Mitochondrial Energetics by Near-Infrared Spectroscopy

Philos Trans R Soc Lond B Biol Sci Jun 29, 1997; 352(1354): 669–676. doi: 10.1098/rstb.1997.0048 

Cunliffe WJ, Goulden V

Phototherapy and acne vulgaris

Br J Dermatol 2000 May;142(5):855-6

Demura S, Noguchi T, Matsuzawa J

Comparison in the Effect of Linear Polarized Near-Infrared Light Irradiation and Light Exercise on Shoulder Joint Flexibility

J Mol Cell Cardiol Jan 2009; 46(1): 4–14. doi: 10.1016/j.yjmcc.2008.09.707 

Demura S, Yamaji S, Ikemoto Y

Effect of linear polarized near-infrared light irradiation on flexibility of shoulder and ankle joints

J Sports Med Phys Fitness 2002 Dec;42(4):438-45 

Eduardo Cde P, Bezinelli LM, Eduardo Fde P, da Graça Lopes RM, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M

Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up

Lasers Med Sci 2012 Sep;27(5):1077-83. doi: 10.1007/s10103-011-1019-6. Epub 2011 Nov 16 

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT

Therapeutic photobiomodulation for methanol-induced retinal toxicity

Proc Natl Acad Sci U S A 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100 

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT

Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy

Mitochondrion 2004 Sep;4(5-6):559-67 

Falaki F, Nejat AH, Dalirsani Z

The Effect of Low-level Laser Therapy on Trigeminal Neuralgia: A Review of Literature

Journal of Dental Research, Dental Clinics, Dental Prospects 2014;8(1):1-5. doi:10.5681/joddd.2014.001 

Ferraresi C, Hamblin MR, Parizotto NA

Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light

Photonics and lasers in medicine 2012;1(4):267-286. doi:10.1515/plm-2012-0032 

Fessenden J

Tuning light to kill deep cancer tumors

UMass Medical School Communications 41913 

Frank S, Oliver L, Lebreton-De Coster C, Moreau C, Lecabellec MT, Michel L, Vallette FM, Dubertret L, Coulomb B

Infrared radiation affects the mitochondrial pathway of apoptosis in human fibroblasts

J Invest Dermatol 2004 Nov;123(5):823-31 

Goldberg DJ, Russell BA

Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris

J Cosmet Laser Ther 2006 Jun;8(2):71-5 

Gomes LE, Dalmarco EM, André ES

The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model

Photomed Laser Surg. 2012 Nov; 30(11):642-7 

Hamblin M

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

AIMS Biophysics 4(3): 337-361. (May 2017); DOI: 10.3934/biophy.2017.3.337 

Hamblin M, Demidova T

Mechanisms of low level light therapy

Proc. SPIE 6140, Mechanisms for Low-Light Therapy 614001 (Feb 2006); doi:10.1117/12.646294 

Hamblin MR

Shining light on the head: Photobiomodulation for brain disorders

BBA Clin. 2016 Oct 1; 6:113–124

Hamblin MR, Nelson ST, Strahan JR

Photobiomodulation and Cancer: What Is the Truth?

Photomed Laser Surg. 2018 May; 36(5):241-245 

Hanna R, Dalvi S, Sălăgean T, Bordea IR, Benedicenti S

Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical Review

Antioxidants (Basel) 2020;9(9):875

Hopkins JT, McLoda TA, Seegmiller JG, David Baxter G

Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Journal of Athletic Training 2004;39(3):223-229 

Höfling DB, Chavantes MC, Juliano AB, Cerri GG, Romão R, Yoshimura EM, Chammas MC

Low-level laser therapy in chronic autoimmune thyroiditis: a pilot study

Lasers Surg Med 2010 Aug;42(6):589-96 

Höfling DB, Chavantes MC, Juliano AG, Cerri GG, Knobel M, Yoshimura EM, Chammas MC

Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo-controlled clinical trial

Lasers Med Sci 2013 May;28(3):743-53 

Ibe O, Morency E, Sosa P,Burkow-Heikkinen L

The role of near-infrared light-emitting diodes in aging adults related to inflammation

Healthy Aging Research 2015, 4:24; 10 April 2015 

Jang H, Lee H

Meta-Analysis of Pain Relief Effects by Laser Irradiation on Joint Areas

Photomed Laser Surg 2012;30(8):405-417. doi: 10.1089/pho.2012.3240 

Kligman LH

Photoaging. Manifestations, prevention, and treatment

Clin Geriatr Med 1989 Feb;5(1):235-51 

Lan CC, Wu CS, Chiou MH, Chiang TY, Yu HS

Low-energy helium-neon laser induces melanocyte proliferation via interaction with type IV collagen: visible light as a therapeutic option for vitiligo

Br J Dermatol 2009 Aug;161(2):273-80. doi: 10.1111/j.1365-2133.2009.09152.x. Epub 2009 Apr 30 

Lan CC, Wu CS, Chiou MH, Hsieh PC, Yu HS

Low-energy helium-neon laser induces locomotion of the immature melanoblasts and promotes melanogenesis of the more differentiated melanoblasts: recapitulation of vitiligo repigmentation in vitro

J Invest Dermatol 2006 Sep;126(9):2119-26. Epub 2006 May 11 

Landthaler M, Haina D, Waidelich W

Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light [Article in German]

Fortschr Med 1983 Jun 9;101(22):1039-41 

Leavitt M, Charles G, Heyman E, Michaels D

HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: A randomized, double-blind, sham device-controlled, multicentre trial

Clin Drug Investig 2009;29(5):283-92. doi: 10.2165/00044011-200929050-00001 

Lee SY, Park KH, Choi JW, Kwon JK, Lee DR, Shin MS, Lee JS, You CE, Park MY

A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings

J Photochem Photobiol B 2007 Jul 27;88(1):51-67. Epub 2007 May 1 

Lee SY, You CE, Park MY

Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV

Lasers Surg Med 2007 Feb;39(2):180-8 

Luo L, Sun Z, Zhang L, Li X, Dong Y, Liu TC

Effects of low-level laser therapy on ROS homeostasis and expression of IGF-1 and TGF-β1 in skeletal muscle during the repair process

Lasers Med Sci 2013 May;28(3):725-34. doi: 10.1007/s10103-012-1133-0. Epub 2012 Jun 20 

Maegawa Y, Itoh T, Hosokawa T, Yaegashi K, Nishi M

Effects of near-infrared low-level laser irradiation on microcirculation

Lasers Surg Med 2000;27(5):427-37. doi: 10.1002/1096-9101(2000)27:5<427::AID-LSM1004>3.0.CO;2-A. 

Medrado AP, Soares AP, Santos ET, Reis SR, Andrade ZA

Influence of laser photobiomodulation upon connective tissue remodeling during wound healing

J Photochem Photobiol B 2008 Sep 18;92(3):144-52. doi: 10.1016/j.jphotobiol.2008.05.008. Epub 2008 Jul 7 

Meneguzzo DT, Lopes LA, Pallota R, Soares-Ferreira L, Lopes-Martins RÁ, Ribeiro MS

Prevention and treatment of mice paw edema by near-infrared low-level laser therapy on lymph nodes

Lasers Med Sci 2013 May;28(3):973-80. doi: 10.1007/s10103-012-1163-7. Epub 2012 Aug 23 

Mitsunaga M, Ogawa M, Kosaka N, Rosenblum LT, Choyke PL, Kobayashi H

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Nat Med. 2011 Nov 6; 17:1685–91

Muñoz Sanchez PJ, Capote Femenías JL, Díaz Tejeda A, Tunér J

The effect of 670-nm low laser therapy on herpes simplex type 1

Photomed Laser Surg 2012 Jan;30(1):37-40. doi: 10.1089/pho.2011.3076. Epub 2011 Nov 2 

Nanni CA, Alster TS

Complications of carbon dioxide laser resurfacing. An evaluation of 500 patients

Dermatol Surg 1998 Mar;24(3):315-20

Paasch U, Haedersdal M

Laser systems for ablative fractional resurfacing

Expert Rev Med Devices 2011 Jan;8(1):67-83. doi: 10.1586/erd.10.74 

Papageorgiou P, Katsambas A, Chu A

Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris

Br J Dermatol 2000 May;142(5):973-8

Peoples C, Shaw VE, Stone J, Jeffery G,Baker GE, and Mitrofanis J

Survival of Dopaminergic Amacrine Cells after Near-Infrared Light Treatment in MPTP-Treated Mice

ISRN Neurol 2012; 2012: 850150. doi: 10.5402/2012/850150 

Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M

Low-level laser therapy for wound healing: mechanism and efficacy

Dermatol Surg 2005 Mar;31(3):334-40

Reiter RJ, Ma Q, Sharma R

Melatonin in Mitochondria: Mitigating Clear and Present Dangers

Physiology (Bethesda). 2020 Mar 1;35(2):86-95 

Rojas JC, Gonzalez-Lima F

Low-level light therapy of the eye and brain

Eye and Brain. 2011; 3:49–67

Salehpour F, Farajdokht F, Erfani M, Sadigh-Eteghad S, Shotorbani SS, Hamblin MR, Karimi P, Rasta SH, Mahmoudi J

Transcranial near-infrared photobiomodulation attenuates memory impairment and hippocampal oxidative stress in sleep-deprived mice.

Brain Res. 2018 Mar 1; 1682:36-43

Sasaki GH, Oberg K, Tucker B, Gaston M

The effectiveness and safety of topical PhotoActif phosphatidylcholine-based anti-cellulite gel and LED (red and near-infrared) light on Grade II-III thigh cellulite: a randomized, double-blinded study

J Cosmet Laser Ther 2007 Jun;9(2):87-96 

Satino JL, Markou M

Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

International Journal of Cosmetic Surgery and Aesthetic Dermatology August 2003, 5(2): 113-117. doi:10.1089/153082003769591209 

Sawhney, MK, Hamblin, MR

Low Level Laser (Light) Therapy (LLLT) for Cosmetic Medicine and Dermatology

Wellman Center for Photomedicine, Mass. Gen. Hospital, Boston, MA and Dept. Dermatology, Harvard Med. School, Boston, MA. 

Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety

Behavioral and Brain Functions : BBF. 2009; 5:46 

Schindl A, Neumann R

Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study

J Invest Dermatol 1999 Aug;113(2):221-3 

Schroeder P, Calles C, Benesova T, Macaluso F, Krutmann J

Photoprotection beyond ultraviolet radiation–effective sun protection has to include protection against infrared A radiation-induced skin damage

Skin Pharmacol Physiol 2010;23(1):15-7. doi: 10.1159/000257259. Epub 2010 Jan 14 

Shinhmar H, Hogg C, Neveu M, Jeffery G

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Sci Rep. 2021; 11(22872)

Shukla S, Sahu K, Verma Y, Rao KD, Dube A, Gupta PK

Effect of helium-neon laser irradiation on hair follicle growth cycle of Swiss albino mice

Skin Pharmacol Physiol 2010;23(2):79-85. doi: 10.1159/000265678. Epub 2009 Dec 14 

Sinha RP, Häder DP

UV-induced DNA damage and repair: a review

Photochem Photobiol Sci 2002 Apr;1(4):225-36 

Sriprachya-Anunt S, Fitzpatrick RE, Goldman MP, Smith SR

Infections complicating pulsed carbon dioxide laser resurfacing for photoaged facial skin

Dermatol Surg 1997 Jul;23(7):527-35; discussion 535-6 

Sumen A, Sarsan A, Alkan H, Yildiz N, Ardic F

Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome

J Back Musculoskelet Rehabil 2015;28(1):153-8 

Tanaka Y, Matsuo K, Yuzuriha S

Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians

Clinical, Cosmetic and Investigational Dermatology 2011;4:123-130. doi:10.2147/CCID.S22841 

Taoa H, Hwangb S, Marellia B, Ana B, Moreaua J E, Yanga M, Brencklea M A, Kimb S, Kaplana D L, Rogers J A, Omenetto F G

Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement

PNAS November 24, 2014, doi: 10.1073/pnas.1407743111 

Weiss RA, McDaniel DH, Geronemus RG, Weiss MA, Beasley KL, Munavalli GM, Bellew SG

Clinical experience with light-emitting diode (LED) photomodulation

Dermatol Surg 2005 Sep;31(9 Pt 2):1199-205 

Whelan HT, Buchmann EV, Dhokalia A, Kane MP,Whelan NT, Wong-Riley M, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M

Effect of NASA Light-Emitting Diode Irradiation on Molecular Changes for Wound Healing in Diabetic Mice

J Clin Laser Med Surg April 2003, 21(2): 67-74. doi:10.1089/104454703765035484 

Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ

Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata

Lasers Med Sci 2012 Mar;27(2):431-6. doi: 10.1007/s10103-011-0953-7. Epub 2011 Jul 9 

Wong-Riley M, Liang H, et al

Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins

The Journal of Biological Chemistry February 11, 2005, 280: 4761-4771. doi: 10.1074/jbc.M409650200 

Yang M, Yang Z, Wang P, Sun Z

Current application and future directions of photobiomodulation in central nervous diseases.

Neural Regen Res. 2021; 16(6):1177-1185 

Yeager RL, Oleske DA, Sanders RA, Watkins JB 3rd, Eells JT, Henshel DS

Melatonin as a principal component of red light therapy

Med Hypotheses. 2007;69(2):372-6

Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, Irani S, Shakiba B, Mortaz Hejri SA, Mortaz Hejri SO, Jonaidi A

Low level laser therapy for nonspecific low-back pain

Cochrane Database Syst Rev 2008 Apr 16;(2):CD005107. doi: 10.1002/14651858.CD005107.pub4 

Yu HS, Wu CS, Yu CL, Kao YH, Chiou MH

Helium-neon laser irradiation stimulates migration and proliferation in melanocytes and induces repigmentation in segmental-type vitiligo

J Invest Dermatol 2003 Jan;120(1):56-64 

Yu W, Naim JO, McGowan M, Ippolito K, Lanzafame RJ

Photomodulation of Oxidative Metabolism and Electron Chain Enzymes in Rat Liver Mitochondria

Photochem Photobiol 1997 Dec;66(6):866-71 

Zhang C, Wong-Riley M

Expression and regulation of NMDA receptor subunit R1 and neuronal nitric oxide synthase in cortical neuronal cultures: correlation with cytochrome oxidase

J Neurocytol 1999 Jul;28(7):525-39

Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M

Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism

J Mol Cell Cardiol 2009 Jan;46(1):4-14. doi: 10.1016/j.yjmcc.2008.09.707 

Zhao J, Tian Y, Nie J, Xu J, Liu D

Red light and the sleep quality and endurance performance of Chinese female basketball players

J Athl Train. 2012 Nov-Dec;47(6):673-8 

Zhu Q, Xiao S, Hua Z, Yang D, Hu M, Zhu YT, Zhong H

Near Infrared (NIR) Light Therapy of Eye Diseases: A Review

International journal of medical sciences. 2021 Jan 1; 18(1):109-119 

Zimmerman, S. and Reiter, R

Melatonin and the Optics of the Human Body

Melatonin Research. 2, 1 (Feb. 2019), 138-160 

de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H

Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon

Lasers Med Sci 2015 Jan;30(1):153-8. doi: 10.1007/s10103-014-1636-y. Epub 2014 Jul 29 

Centers For Disease Control and Prevention

CDC Lyme Disease Data

Abou-Hala AZ, Barbosa DG, Marcos RL, et al

Effects of the Infrared Lamp Illumination during the Process of Muscle Fatigue in Rats

RAZ ARCH BIOL TECHNOL 01/2007; 50(3). doi: 10.1590/S1516-89132007000300006 

Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

J Cell Biol 2002 Apr 1;157(1):137-48. Epub 2002 Apr 1 

Bibikova A, Oron U

Promotion of muscle regeneration in the toad (Bufo viridis) gastrocnemius muscle by low-energy laser irradiation

Anat Rec 1993 Mar;235(3):374-80

Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, Yu Y, Greenway FL

Efficacy of low-level laser therapy for body contouring and spot fat reduction

Obes Surg 2011 Jun;21(6):722-9. doi: 10.1007/s11695-010-0126-y 

Chow LS, Albright RC, Bigelow ML, Toffolo G, Cobelli C, Nair KS

Mechanism of insulin’s anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures

Am J Physiol Endocrinol Metab 2006 Oct;291(4):E729-36. Epub 2006 May 16 

Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

J Biol Chem 1995 May 19;270(20):12109-16 

Costa RJ, Crockford MJ, Moore JP, Walsh NP

Heat acclimation responses of an ultra-endurance running group preparing for hot desert-based competition

Eur J Sport Sci 2014;14 Suppl 1:S131-41. doi: 10.1080/17461391.2012.660506. Epub 2012 Mar 19 

Felsing NE, Brasel JA, Cooper DM

Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men

J Clin Endocrinol Metab 1992 Jul;75(1):157-62 

Ferraresi C, Hamblin MR, Parizotto NA

Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light

Photonics and lasers in medicine 2012;1(4):267-286. doi:10.1515/plm-2012-0032 

Ftaiti F, Jemni M, Kacem A, Zaouali MA, Tabka Z, Zbidi A, Grélot L

Effect of hyperthermia and physical activity on circulating growth hormone

Appl Physiol Nutr Metab 2008 Oct;33(5):880-7. doi: 10.1139/H08-073 

Gale GD, Rothbart PJ, Li Y

Infrared therapy for chronic low back pain: a randomized, controlled trial

Pain Res Manag 2006 Autumn;11(3):193-6 

Hamblin M

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

AIMS Biophysics 4(3): 337-361. (May 2017); DOI: 10.3934/biophy.2017.3.337 

King DS, Costill DL, Fink WJ, Hargreaves M, Fielding RA

Muscle metabolism during exercise in the heat in unacclimatized and acclimatized humans

J Appl Physiol (1985) 1985 Nov;59(5):1350-4. doi: 10.1152/jappl.1985.59.5.1350. 

Kirwan JP, Costill DL, Kuipers H, Burrell MJ, Fink WJ, Kovaleski JE, Fielding RA

Substrate utilization in leg muscle of men after heat acclimation

J Appl Physiol (1985) 1987 Jul;63(1):31-5. doi: 10.1152/jappl.1987.63.1.31. 

Louard RJ, Fryburg DA, Gelfand RA, Barrett EJ

Insulin sensitivity of protein and glucose metabolism in human forearm skeletal muscle

J Clin Invest. 1992 Dec;90(6):2348-54. doi: 10.1172/JCI116124. 

Luo L, Sun Z, Zhang L, Li X, Dong Y, Liu TC

Effects of low-level laser therapy on ROS homeostasis and expression of IGF-1 and TGF-β1 in skeletal muscle during the repair process

Lasers Med Sci 2013 May;28(3):725-34. doi: 10.1007/s10103-012-1133-0. Epub 2012 Jun 20 

Medrado AP, Soares AP, Santos ET, Reis SR, Andrade ZA

Influence of laser photobiomodulation upon connective tissue remodeling during wound healing

J Photochem Photobiol B 2008 Sep 18;92(3):144-52. doi: 10.1016/j.jphotobiol.2008.05.008. Epub 2008 Jul 7 

Naito H, Powers SK, Demirel HA, Sugiura T, Dodd SL, Aoki J

Heat stress attenuates skeletal muscle atrophy in hindlimb-unweighted rats

J Appl Physiol (1985) 2000 Jan;88(1):359-63 

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Pedersen BK

Muscle as a secretory organ

Compr Physiol 2013 Jul;3(3):1337-62. doi: 10.1002/cphy.c120033 

Savard GK, Nielsen B, Laszczynska J, Larsen BE, Saltin B

Muscle blood flow is not reduced in humans during moderate exercise and heat stress

J Appl Physiol (1985) 1988 Feb;64(2):649-57 

Scoon GS, Hopkins WG, Mayhew S, Cotter JD

Effect of post-exercise sauna bathing on the endurance performance of competitive male runners

J Sci Med Sport 2007 Aug;10(4):259-62. Epub 2006 Jul 31 

Selsby JT, Dodd SL

Heat treatment reduces oxidative stress and protects muscle mass during immobilization

Am J Physiol Regul Integr Comp Physiol 2005 Jul;289(1):R134-9. Epub 2005 Mar 10 

Selsby JT, Rother S, Tsuda S, Pracash O, Quindry J, Dodd SL

Intermittent hyperthermia enhances skeletal muscle regrowth and attenuates oxidative damage following reloading

J Appl Physiol (1985) 2007 Apr;102(4):1702-7. Epub 2006 Nov 16 

Sumen A, Sarsan A, Alkan H, Yildiz N, Ardic F

Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome

J Back Musculoskelet Rehabil 2015;28(1):153-8 

Van Praag H, Christie BR, Sejnowski TJ, Gage FH

Running enhances neurogenesis, learning, and long-term potentiation in mice

Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13427-13431 

Velloso CP

Regulation of muscle mass by growth hormone and IGF-I

British Journal of Pharmacology 2008;154(3):557-568. doi:10.1038/bjp.2008.153 

Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, Irani S, Shakiba B, Mortaz Hejri SA, Mortaz Hejri SO, Jonaidi A

Low level laser therapy for nonspecific low-back pain

Cochrane Database Syst Rev 2008 Apr 16;(2):CD005107. doi: 10.1002/14651858.CD005107.pub4 

de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H

Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon

Lasers Med Sci 2015 Jan;30(1):153-8. doi: 10.1007/s10103-014-1636-y. Epub 2014 Jul 29 

Clark IA, Vissel B

Inflammation-sleep interface in brain disease: TNF, insulin, orexin

J Neuroinflammation. 2014 Mar 21; 11:51 

Duveau V, Arthaud S, Serre H, Rougier A, Le Gal La Salle G

Transient hyperthermia protects against subsequent seizures and epilepsy-induced cell damage in the rat

Neurobiol Dis. 2005 Jun-Jul; 19(1-2):142-9 

Eells JT, Henry MM, Summerfelt P, Wong-Riley MTT, Buchmann EV, Kane M, Whelan NT, and Whelan HT

Therapeutic photobiomodulation for methanol-induced retinal toxicity

Proc Natl Acad Sci U S A 2003 Mar 18; 100(6): 3439–3444. Published online 2003 Mar 7. doi: 10.1073/pnas.0534746100 

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT

Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy

Mitochondrion 2004 Sep;4(5-6):559-67 

Falaki F, Nejat AH, Dalirsani Z

The Effect of Low-level Laser Therapy on Trigeminal Neuralgia: A Review of Literature

Journal of Dental Research, Dental Clinics, Dental Prospects 2014;8(1):1-5. doi:10.5681/joddd.2014.001 

Gale GD, Rothbart PJ, Li Y

Infrared therapy for chronic low back pain: a randomized, controlled trial

Pain Res Manag 2006 Autumn;11(3):193-6 

Goekint M, Roelands B, Heyman E, Njemini R, Meeusen R

Influence of citalopram and environmental temperature on exercise-induced changes in BDNF

Neurosci Lett 2011 Apr 25;494(2):150-4. doi: 10.1016/j.neulet.2011.03.001. Epub 2011 Mar 6 

Gomes LE, Dalmarco EM, André ES

The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model

Photomed Laser Surg. 2012 Nov; 30(11):642-7 

Gregg C, Shikar V, Larsen P, Mak G, Chojnacki A, Yong VW, Weiss S

White matter plasticity and enhanced remyelination in the maternal CNS

J Neurosci 2007 Feb 21;27(8):1812-23 

Ham WT Jr, Mueller HA, Ruffolo JJ Jr, Clarke AM

Sensitivity of the retina to radiation damage as a function of wavelength

Photochem Photobiol 1979 Apr;29(4):735-43 

Laukkanen T, Kunutsor S, Kauhanen J, Laukkanen JA

Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men

Age Ageing. 2017 Mar 1; 46(2):245-249 

Lundgren J, Smith ML, Blennow G, Siesjö BK

Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage

Exp Brain Res. 1994; 99(1):43-55

Lydahl E, Philipson B

Infrared radiation and cataract II. Epidemiologic investigation of glass workers

Acta Ophthalmol (Copenh) 1984 Dec;62(6):976-92 

Maniam J, Morris MJ

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

Psychoneuroendocrinology 2010 Nov;35(10):1553-64. doi: 10.1016/j.psyneuen.2010.05.012. Epub 2010 Jul 1. 

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Rojas JC, Gonzalez-Lima F

Low-level light therapy of the eye and brain

Eye and Brain. 2011; 3:49–67

Salbaum JM, Cirelli C, Walcott E, Krushel LA, Edelman GM, Tononi G

Chlorotoxin-mediated disinhibition of noradrenergic locus coeruleus neurons using a conditional transgenic approach

Brain Res 2004 Jul 30;1016(1):20-32

Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety

Behavioral and Brain Functions : BBF. 2009; 5:46 

Van Praag H, Christie BR, Sejnowski TJ, Gage FH

Running enhances neurogenesis, learning, and long-term potentiation in mice

Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13427-13431 

Voke , J

Radiation effects on the eye

Optometry Today 1999; 8:30-35

Wong-Riley M, Liang H, et al

Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins

The Journal of Biological Chemistry February 11, 2005, 280: 4761-4771. doi: 10.1074/jbc.M409650200 

Xin L, Geller EB, Adler MW

Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain

J Pharmacol Exp Ther. 1997 Apr; 281(1):499-507 

Yang M, Yang Z, Wang P, Sun Z

Current application and future directions of photobiomodulation in central nervous diseases.

Neural Regen Res. 2021; 16(6):1177-1185 

Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, Irani S, Shakiba B, Mortaz Hejri SA, Mortaz Hejri SO, Jonaidi A

Low level laser therapy for nonspecific low-back pain

Cochrane Database Syst Rev 2008 Apr 16;(2):CD005107. doi: 10.1002/14651858.CD005107.pub4 

Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA

Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials

Photomed Laser Surg 2006 Apr;24(2):158-68 

Bjordal JM, Lopes-Martins RA, Joensen J, et al

A systematic review with procedural assessments and meta-analysis of Low Level Laser Therapy in lateral elbow tendinopathy (tennis elbow)

BMC Musculoskeletal Disorders 2008;9:75. doi:10.1186/1471-2474-9-75 

Chow RT, Johnson MI, PhD, Lopes-Martins R, Bjordal JM

Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials

Lancet 2009 Dec 5;374(9705):1897-908. doi: 10.1016/S0140-6736(09)61522-1. Epub 2009 Nov 13 

Gale GD, Rothbart PJ, Li Y

Infrared therapy for chronic low back pain: a randomized, controlled trial

Pain Res Manag 2006 Autumn;11(3):193-6 

Hamblin M

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

AIMS Biophysics 4(3): 337-361. (May 2017); DOI: 10.3934/biophy.2017.3.337 

Jang H, Lee H

Meta-Analysis of Pain Relief Effects by Laser Irradiation on Joint Areas

Photomed Laser Surg 2012;30(8):405-417. doi: 10.1089/pho.2012.3240 

Landthaler M, Haina D, Waidelich W

Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light [Article in German]

Fortschr Med 1983 Jun 9;101(22):1039-41 

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Sumen A, Sarsan A, Alkan H, Yildiz N, Ardic F

Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome

J Back Musculoskelet Rehabil 2015;28(1):153-8 

Xin L, Geller EB, Adler MW

Body temperature and analgesic effects of selective mu and kappa opioid receptor agonists microdialyzed into rat brain

J Pharmacol Exp Ther. 1997 Apr; 281(1):499-507 

Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, Irani S, Shakiba B, Mortaz Hejri SA, Mortaz Hejri SO, Jonaidi A

Low level laser therapy for nonspecific low-back pain

Cochrane Database Syst Rev 2008 Apr 16;(2):CD005107. doi: 10.1002/14651858.CD005107.pub4 

Hamblin MR

Shining light on the head: Photobiomodulation for brain disorders

BBA Clin. 2016 Oct 1; 6:113–124

Maniam J, Morris MJ

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: Role of hippocampus

Psychoneuroendocrinology 2010 Nov;35(10):1553-64. doi: 10.1016/j.psyneuen.2010.05.012. Epub 2010 Jul 1. 

Pall ML

How can we cure NO/ONOO− cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others

Townsend Lett. 2010 Feb 19; 75–84

Rojas JC, Gonzalez-Lima F

Low-level light therapy of the eye and brain

Eye and Brain. 2011; 3:49–67

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR

Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety

Behavioral and Brain Functions : BBF. 2009; 5:46 

Yang M, Yang Z, Wang P, Sun Z

Current application and future directions of photobiomodulation in central nervous diseases.

Neural Regen Res. 2021; 16(6):1177-1185 

Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring

Semin Cutan Med Surg 2013 Mar;32(1):41-52 

Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

J Cell Biol 2002 Apr 1;157(1):137-48. Epub 2002 Apr 1 

Bibikova A, Oron U

Promotion of muscle regeneration in the toad (Bufo viridis) gastrocnemius muscle by low-energy laser irradiation

Anat Rec 1993 Mar;235(3):374-80

Christensen SE, Jørgensen OL, et al

Characterization of Growth Hormone Release in Response to External Heating

Acta Endocrinol (Copenh) 1984 Nov; 107(3): 295-301 

Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

J Biol Chem 1995 May 19;270(20):12109-16 

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT

Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy

Mitochondrion 2004 Sep;4(5-6):559-67 

Felsing NE, Brasel JA, Cooper DM

Effect of Low and High Intensity Exercise on Circulating Growth Hormone in Men

J Clin Endocrinol Metab 1992 Jul;75(1):157-62 

Ftaiti F, Jemni M, Kacem A, Zaouali MA, Tabka Z, Zbidi A, Grélot L

Effect of hyperthermia and physical activity on circulating growth hormone

Appl Physiol Nutr Metab 2008 Oct;33(5):880-7. doi: 10.1139/H08-073 

Gomes LE, Dalmarco EM, André ES

The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model

Photomed Laser Surg. 2012 Nov; 30(11):642-7 

Healy ML, Gibney J, Russell-Jones DL, Pentecost C, Croos P, Sönksen PH, Umpleby AM

High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes

J Clin Endocrinol Metab 2003 Nov;88(11):5221-6 

Ho KY, Veldhuis JD, Johnson ML, et al

Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man

Journal of Clinical Investigation 1988;81(4):968-975 

Hopkins JT, McLoda TA, Seegmiller JG, David Baxter G

Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Journal of Athletic Training 2004;39(3):223-229 

Liu W, Wang DR, Cao YL

TGF-beta: a fibrotic factor in wound scarring and a potential target for anti-scarring gene therapy

Curr Gene Ther 2004 Mar;4(1):123-36

Medrado AP, Soares AP, Santos ET, Reis SR, Andrade ZA

Influence of laser photobiomodulation upon connective tissue remodeling during wound healing

J Photochem Photobiol B 2008 Sep 18;92(3):144-52. doi: 10.1016/j.jphotobiol.2008.05.008. Epub 2008 Jul 7 

Niwa Y, Kawahira K, Matsumoto K

Effect of far infrared ray emitting products and stones on human leukocyte functions, lipid peroxidation, the growth of tumor on mice, drug-induced hepatitis rat, and clinical course and serum lipid peroxide levels of rheumatoid arthritis patients [in Japanese]

Japanese Journal of Inflammation. 1996; 16:425-436 

Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M

Low-level laser therapy for wound healing: mechanism and efficacy

Dermatol Surg 2005 Mar;31(3):334-40

Satino JL, Markou M

Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

International Journal of Cosmetic Surgery and Aesthetic Dermatology August 2003, 5(2): 113-117. doi:10.1089/153082003769591209 

Selsby JT, Rother S, Tsuda S, Pracash O, Quindry J, Dodd SL

Intermittent hyperthermia enhances skeletal muscle regrowth and attenuates oxidative damage following reloading

J Appl Physiol (1985) 2007 Apr;102(4):1702-7. Epub 2006 Nov 16 

Shinhmar H, Hogg C, Neveu M, Jeffery G

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Sci Rep. 2021; 11(22872)

Shukla S, Sahu K, Verma Y, Rao KD, Dube A, Gupta PK

Effect of helium-neon laser irradiation on hair follicle growth cycle of Swiss albino mice

Skin Pharmacol Physiol 2010;23(2):79-85. doi: 10.1159/000265678. Epub 2009 Dec 14 

Velloso CP

Regulation of muscle mass by growth hormone and IGF-I

British Journal of Pharmacology 2008;154(3):557-568. doi:10.1038/bjp.2008.153 

Whelan HT, Buchmann EV, Dhokalia A, Kane MP,Whelan NT, Wong-Riley M, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M

Effect of NASA Light-Emitting Diode Irradiation on Molecular Changes for Wound Healing in Diabetic Mice

J Clin Laser Med Surg April 2003, 21(2): 67-74. doi:10.1089/104454703765035484 

Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ

Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata

Lasers Med Sci 2012 Mar;27(2):431-6. doi: 10.1007/s10103-011-0953-7. Epub 2011 Jul 9 

Yeager RL, Oleske DA, Sanders RA, Watkins JB 3rd, Eells JT, Henshel DS

Melatonin as a principal component of red light therapy

Med Hypotheses. 2007;69(2):372-6

Zhu Q, Xiao S, Hua Z, Yang D, Hu M, Zhu YT, Zhong H

Near Infrared (NIR) Light Therapy of Eye Diseases: A Review

International journal of medical sciences. 2021 Jan 1; 18(1):109-119 

de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H

Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon

Lasers Med Sci 2015 Jan;30(1):153-8. doi: 10.1007/s10103-014-1636-y. Epub 2014 Jul 29 

Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J

IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells

J Interferon Cytokine Res 2009 May;29(5):273-84. doi: 10.1089/jir.2008.0076 

Shen RN, Hornback NB, Shidnia H, Shupe RE, Brahmi Z

Whole-body hyperthermia decreases lung metastases in lung tumor-bearing mice, possibly via a mechanism involving natural killer cells

J Clin Immunol 1987 May;7(3):246-53

Duveau V, Arthaud S, Serre H, Rougier A, Le Gal La Salle G

Transient hyperthermia protects against subsequent seizures and epilepsy-induced cell damage in the rat

Neurobiol Dis. 2005 Jun-Jul; 19(1-2):142-9 

Lundgren J, Smith ML, Blennow G, Siesjö BK

Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage

Exp Brain Res. 1994; 99(1):43-55

Ablon G

Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings

Photomed Laser Surg 2010 Feb;28(1):141-6. doi: 10.1089/pho.2009.2484. 

Airan LE, Hruza G

Current lasers in skin resurfacing

Facial Plast Surg Clin North Am 2005 Feb;13(1):127-39 

Applegate LA, Scaletta C, Panizzon R, Frenk E, Hohlfeld P, Schwarzkopf S

Induction of the putative protective protein ferritin by infrared radiation: implications in skin repair

Int J Mol Med 2000 Mar;5(3):247-51

Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring

Semin Cutan Med Surg 2013 Mar;32(1):41-52 

Barolet D, Boucher A

Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series

Lasers Surg Med 2010 Aug;42(6):597-601. doi: 10.1002/lsm.20952 

Barolet D, Christiaens F, Hamblin MR

Infrared and skin: Friend or foe

J Photochem Photobiol B. 2016 Feb; 155:78-85 

Barolet D, Roberge CJ, Auger FA, Boucher A, Germain L

Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study

J Invest Dermatol 2009 Dec;129(12):2751-9. doi: 10.1038/jid.2009.186. Epub 2009 Jul 9 

Bello-Silva MS, de Freitas PM, Aranha AC, Lage-Marques JL, Simões A, de Paula Eduardo C

Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection

Photomed Laser Surg 2010 Feb;28(1):135-9. doi: 10.1089/pho.2008.2458 

Branham GH, Thomas JR

Rejuvenation of the skin surface: chemical peel and dermabrasion

Facial Plast Surg 1996 Apr;12(2):125-33 

Calles C, Schneider M, Macaluso F, Benesova T, Krutmann J, Schroeder P

Infrared A radiation influences the skin fibroblast transcriptome: mechanisms and consequences

J Invest Dermatol 2010 Jun;130(6):1524-36. doi: 10.1038/jid.2010.9. Epub 2010 Feb 4 

Cherniaev, IuS

Investigation of the permeability of human skin to infrared radiation [Article in Russian]

Gig Sanit 1965 Dec;30(12):20-4

Cunliffe WJ, Goulden V

Phototherapy and acne vulgaris

Br J Dermatol 2000 May;142(5):855-6

Eduardo Cde P, Bezinelli LM, Eduardo Fde P, da Graça Lopes RM, Ramalho KM, Bello-Silva MS, Esteves-Oliveira M

Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up

Lasers Med Sci 2012 Sep;27(5):1077-83. doi: 10.1007/s10103-011-1019-6. Epub 2011 Nov 16 

Goldberg DJ, Russell BA

Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris

J Cosmet Laser Ther 2006 Jun;8(2):71-5 

Landthaler M, Haina D, Waidelich W

Treatment of zoster, post-zoster pain and herpes simplex recidivans in loco with laser light [Article in German]

Fortschr Med 1983 Jun 9;101(22):1039-41 

Lee SY, Park KH, Choi JW, Kwon JK, Lee DR, Shin MS, Lee JS, You CE, Park MY

A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings

J Photochem Photobiol B 2007 Jul 27;88(1):51-67. Epub 2007 May 1 

Lee SY, You CE, Park MY

Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV

Lasers Surg Med 2007 Feb;39(2):180-8 

Muñoz Sanchez PJ, Capote Femenías JL, Díaz Tejeda A, Tunér J

The effect of 670-nm low laser therapy on herpes simplex type 1

Photomed Laser Surg 2012 Jan;30(1):37-40. doi: 10.1089/pho.2011.3076. Epub 2011 Nov 2 

Papageorgiou P, Katsambas A, Chu A

Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris

Br J Dermatol 2000 May;142(5):973-8

Sadick NS

Handheld LED array device in the treatment of acne vulgaris

J Drugs Dermatol 2008 Apr;7(4):347-50 

Schindl A, Neumann R

Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study

J Invest Dermatol 1999 Aug;113(2):221-3 

Schroeder P, Calles C, Benesova T, Macaluso F, Krutmann J

Photoprotection beyond ultraviolet radiation–effective sun protection has to include protection against infrared A radiation-induced skin damage

Skin Pharmacol Physiol 2010;23(1):15-7. doi: 10.1159/000257259. Epub 2010 Jan 14 

Sriprachya-Anunt S, Fitzpatrick RE, Goldman MP, Smith SR

Infections complicating pulsed carbon dioxide laser resurfacing for photoaged facial skin

Dermatol Surg 1997 Jul;23(7):527-35; discussion 535-6 

Takema Y, Yorimoto Y, Kawai M, Imokawa G

Age-related changes in the elastic properties and thickness of human facial skin

Br J Dermatol 1994 Nov;131(5):641-8

Tanaka Y, Matsuo K, Yuzuriha S

Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians

Clinical, Cosmetic and Investigational Dermatology 2011;4:123-130. doi:10.2147/CCID.S22841 

Clark IA, Vissel B

Inflammation-sleep interface in brain disease: TNF, insulin, orexin

J Neuroinflammation. 2014 Mar 21; 11:51 

Laukkanen JA, Kunutsor SK

The multifaceted benefits of passive heat therapies for extending the healthspan: A comprehensive review with a focus on Finnish sauna

Temperature (Austin). 2024 Feb 25;11(1):27-51. doi: 10.1080/23328940.2023.2300623. PMID: 38577299; PMCID: PMC10989710.

Reiter RJ, Ma Q, Sharma R

Melatonin in Mitochondria: Mitigating Clear and Present Dangers

Physiology (Bethesda). 2020 Mar 1;35(2):86-95 

Ross GH, Sternquist MC

Methamphetamine exposure and chronic illness in police officers: significant improvement with sauna-based detoxification therapy.

Toxicol Ind Health. 2012;28(8):758-768 

Salehpour F, Farajdokht F, Erfani M, Sadigh-Eteghad S, Shotorbani SS, Hamblin MR, Karimi P, Rasta SH, Mahmoudi J

Transcranial near-infrared photobiomodulation attenuates memory impairment and hippocampal oxidative stress in sleep-deprived mice.

Brain Res. 2018 Mar 1; 1682:36-43

Yeager RL, Oleske DA, Sanders RA, Watkins JB 3rd, Eells JT, Henshel DS

Melatonin as a principal component of red light therapy

Med Hypotheses. 2007;69(2):372-6

Zhao J, Tian Y, Nie J, Xu J, Liu D

Red light and the sleep quality and endurance performance of Chinese female basketball players

J Athl Train. 2012 Nov-Dec;47(6):673-8 

Zimmerman, S. and Reiter, R

Melatonin and the Optics of the Human Body

Melatonin Research. 2, 1 (Feb. 2019), 138-160 

Alster TS, Tanzi EL

Cellulite treatment using a novel combination radiofrequency, infrared light, and mechanical tissue manipulation device

J Cosmet Laser Ther 2005 Jun;7(2):81-5 

Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, Yu Y, Greenway FL

Efficacy of low-level laser therapy for body contouring and spot fat reduction

Obes Surg 2011 Jun;21(6):722-9. doi: 10.1007/s11695-010-0126-y 

Möckel F, Hoffmann G, Obermüller R, Drobnik W, Schmitz G

Influence of water-filtered infrared-A (wIRA) on reduction of local fat and body weight by physical exercise

Ger Med Sci 2006; 4: Doc05

Rossi AB, Vergnanini AL

Cellulite: a review

J Eur Acad Dermatol Venereol 2000(July); 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x 

What is Red Light Therapy? Benefits, Uses & More

 What is Red Light Therapy? Benefits, Uses & More - Clearlight Infrared Saunas